pediatrician


Infusion Services

Providing clinical services to patients with complex conditions

InfuCare Rx is committed to providing unparalleled clinical services to patients with complex conditions such as primary immunodeficiency diseases, autoimmune disorders and hemophilia.

Physicians

Access to all immunoglobulin (IG) brands, allows us to individualize the care plans for each of your patients. Regular communication regarding patient compliance, outcomes, and potential side effects enables us to quickly address any issues. As soon as we receive a patient’s first prescription, one of our pharmacists or nurses will schedule an introductory consultation with them to discuss the treatment plan, dosing and potential side effects. We get to know your patients and work with them to meet their medical needs.

Insurance Companies

Our expert reimbursement team will take all the necessary steps to get written authorization from your insurance company prior to starting treatment. InfuCare Rx is contracted with many managed care organizations, the majority of private and commercial insurance carriers, pharmacy benefit management (PBMs) plans, and Medicare and Medicaid programs.

Pharmaceutical Manufacturers

We work with our manufacturing partners to help educate patients about their disease states and therapy management. Our reimbursement specialists and pharmacists work closely with our partners to maximize patient’s copay assistance through the manufacturer’s programs to lessen patient’s out of pocket costs.

What is immunoglobulin therapy?

Immunoglobulin [ee-mu-no-GLOB-u-lin] or IG has been utilized for decades for the treatment and prevention of a number of conditions. Understanding the process of IG therapy can help you take control of your health and improve your quality of life.

Immunoglobulins, also known as antibodies, are produced by the body to signal the immune system to attack unhealthy or “bad” cells, such as viruses or bacteria. You can think of immunoglobulin as your own personal army that fight off foreign invaders and protect you against illness. This army is made up of protectors (B cells, T cells, immunoglobulin, phagocytes and complement). They all work together to help protect our bodies against infections. When antibody molecules recognize a foreign invader or antigen, they physically attach or bind to the pathogens (i.e. viruses, bacteria and fungi). This sets off a complex chain of events, but ultimately the antibodies work to destroy the invaders.

Immunoglobulin consists of ninety to ninety eight percent immunoglobulin G (IgG). The remainder is made up of small amounts of other antibodies (IgA, IgE and IgM). Today, there are many different brands of immunoglobulin available. The major differences between the brands are IgA content, the sugar found in the solution and the method utilized to clean the product.

Today, immunoglobulin therapy is generally administered in two ways:

1. Intravenous [in-tra-VEEN-us] or IVIG is administered directly into the vein.
2. Subcutaneous [sub-cue-TAY-nee-us] or SCIG is given under the skin.

What is intravenous immunoglobulin therapy?

Intravenous immunoglobulin is administered directly into the vein. Your infusion certified nurse will administer your intravenous immunoglobulin therapy and stay with you for the duration of your treatment. Our nurse is there to assist you every step of the way to ensure that you are receiving the correct dose of your medication, monitor how you are feeling, make sure that you are comfortable, and answer any questions or concerns that you may have. Remember, you are not alone. There are many patients receiving intravenous immunoglobulin therapy and, still living an active, full life.

What is immunoglobulin used for?

There are several FDA-approved uses for immunoglobulin therapy, however, there are more disease states that are not FDA -approved but are standardly treated and respond to immunoglobulin therapy. For example, immunoglobulin therapy has been proven to be effective in the treatment of certain immune deficiency diseases and autoimmune disorders.

There are many resources and organizations available to provide assistance, support, advocacy and information:

What is subcutaneous immunoglobulin therapy?

Subcutaneous immunoglobulin is given under the skin. Your infusion certified nurse will initially administer your subcutaneous immunoglobulin therapy, but will then teach you to administer it independently when you are comfortable. Our nurse is there to assist you every step of the way to ensure that you are receiving the correct dose of your medication, monitor how you are feeling, and answer any questions or concerns that you may have. Remember, you are not alone. There are many patients receiving subcutaneous immunoglobulin therapy and still living an active, full life.

What is subcutaneous immunoglobulin used for?

Presently subcutaneous immunoglobulin is FDA-approved for primary immunodeficiency diseases (PI). Primary immunodeficiency is a genetic condition comprised of a group of more than 250 rare, chronic disorders in which part of the body’s immune system is missing or not functioning properly. This is considered replacement therapy because the body is unable to produce enough of its own immunoglobulins to fight off infections.

In the United States alone, up to 500,000 people are affected by one of the primary immunodeficiency diseases. Primary immunodeficiency often goes untreated because there are no unique or specific symptoms. Symptoms can range from mild to severe and can be mistaken for ordinary infections of the sinuses, ears or lungs. It can also cause gastrointestinal problems and joint inflammation.

Below is a list of the ten warning signs of primary immunodeficiency:

1. Four or more new ear infections within a year
2. Two or more serious sinus infections within a year
3. Two or more months on antibiotics with little effect
4. Two or more pneumonias within a year
5. Failure of an infant to gain weight or grow normally
6. Recurrent, deep skin or organ abscesses
7. Persistent thrush in mouth or fungal infection on skin
8. Need for intravenous antibiotics to clear infections
9. Two or more deep-seated infections including septicemia
10. A family history of primary immunodeficiency

Once properly diagnosed, your physician may prescribe subcutaneous immunoglobulin therapy. Having PI affects your overall health, therefore, it is important to adhere to a regular schedule for receiving your treatment.

How is subcutaneous immunoglobulin therapy administered?

For subcutaneous immunoglobulin administration, one or more small needles are placed under the skin and the medication is infused. Subcutaneous treatments are given more frequently (i.e. weekly, every two or three weeks, or monthly) as opposed to intravenous immunoglobulin infusions, which are commonly given every three to four weeks. Subcutaneous immunoglobulin administration is ideal for patients that require a lower dose, as the skin can quickly and safely absorb the volume.

The needle used for subcutaneous immunoglobulin is very short and thin; just long enough to reach the subcutaneous tissue. It is important that the correct needle length is utilized to minimize site reactions. Your nurse will educate and instruct you on how to properly administer your subcutaneous immunoglobulin therapy, so that you will become confident in self-administration. This will allow you the freedom and flexibility to infuse wherever and whenever it is most convenient for you.

Subcutaneous immunoglobulin treatment is administered using an ambulatory pump. Most patients receive their infusions over one to two hours, but others may need a longerinfusion time to minimize site reactions. Initially, the rate can be adjusted to determine the appropriate volume based on patient’s tolerance. The final rate will then be determined between you and your nurse.

There are many resources and organizations available to provide assistance, support, advocacy and information:

What is hemophilia?

Hemophilia, however rare, is the most common bleeding disorder in which the blood does not clot properly. People with hemophilia are missing one of their clotting factors. Clotting factors are different proteins in the blood that help to stop bleeding. Hemophilia may cause prolonged bleeding after an injury, surgery or a dental procedure. Bleeding may also occur internally in the joints, muscles, brain or other organs of the body.

The two main types of hemophilia are A and B. With hemophilia A being the most common type, it affects nine out of ten people with the disorder. Hemophilia A, also known as classic hemophilia, occurs when a person has low levels of, or is completely lacking, clotting factor VIII (8). People with hemophilia B, also known as Christmas disease, have low levels of, or are completely lacking, clotting factor IX (9). Both forms occur more often in males than females, with one in 5,000 males born each year with the disorder.

What causes hemophilia?

Hemophilia is generally inherited, which means the disorder is caused by a defect in one of the genes that determines how the body makes blood clotting factor VIII or IX. Only the X chromosome carries the genes related to these clotting factors. Therefore, a male that has a defect on his X chromosome will have hemophilia. A female has two X chromosomes, so she must have the defect on both of her X chromosomes to have hemophilia. This rarely occurs in females and is why hemophilia is more common in males.

Although rare, hemophilia can be acquired, which means a person develops the disorder over time. This may occur if a person forms antibodies that attack and prevent the clotting factors from working.

Treatment of bleeding disorders

The most effective way to treat hemophilia is to replace the missing blood clotting factors, which enables the blood to clot properly. These therapies can be used regularly to prevent bleeds or when a person is actively bleeding.

There are many resources and organizations available to provide assistance, support, advocacy and information:

National Hemophilia Foundation
Hemophilia Federation of America


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We coordinate every step of the process, working closely with physicians, insurance companies and pharmaceutical manufacturers to optimize treatment outcomes for our patients. We are proud to back these claims with unparalleled patient and prescriber satisfaction.